Peer-reviewed research articles:

2023

Maes ME, Colombo G, Schoot Uiterkamp FE, Sternberg F, Venturino A, Pohl EE, Siegert S, Mitochondrial network adaptations of microglia reveal sex-specific stress response after injury and UCP2 knockout”, iScience, 2023 Aug 29;26(10):107780

Michalska JM, Lyudchik J, Velicky P, Štefaničková H, Watson JF, Cenameri A, Sommer C, Amberg N, Venturino A, Roessler K, Czech T, Höftberger R, Siegert S, Novarino G, Jonas P, Danzl JG “Imaging brain tissue architecture across millimeter to nanometer scales”, Nature Biotechnology, 2023. https://doi.org/10.1038/s41587-023-01911-8

2022

Hübschmann V, Korkut-Demirbaş M, Siegert S, „Assessing in vitro microglia identity and function by immunostaining, phagocytosis, calcium activity, and inflammation assay”, STAR Protocols, 2022 accepted. https://doi.org/10.1016/j.xpro.2022.101866

Colombo G, Cubero RJA, Kanari L, Venturino A, Schulz R, Scolamiero M, Agerberg J, Mathys H, Tsai L-H, Chachólsk W, Hess K, Siegert S, “A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes”, Nature neuroscience, 2022 Sep 30. https://doi.org/10.1038/s41593-022-011676

Schulz R, Korkut-Demirbaş M, Venturino AColombo G, Siegert S, “Chimeric GPCRs mimic distinct signaling pathways and modulate microglia responses”, Nature Communications, 2022, 13(1):4728, https://doi.org/10.1038/s41467-022-32390-1 

Bartalska K, Hübschmann V, Korkut-Demirbaş M, Cubero RJA, Venturino A, Rössler K, Czech T, Siegert S, “A systematic characterization of microglia-like cell occurrence during retinal organoid differentiation”, iScience, 2022, 25(7):104580, https://doi.org/10.1016/j.isci.2022.104580

2021

Venturino A, Schulz R, de Jesus-Cortex H, Reilly-Andujar F, Maes ME, Nagy B, Cubero RJA, Colombo G, Schoot Uiterkamp FE, Bear M, Siegert S, “Microglia dismantle mature perineuronal nets upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain”, Cell Reports, 2021, 36(1):109313, https://doi.org/10.1016/j.celrep.2021.109313

Venturino A, Siegert S, “Minimally-invasive methods and quantification for microglia-mediated perineuronal net disassembly”, STAR Protocols, 2021; 2(4); 101012, https://doi.org/10.1016/j.xpro.2021.101012

Maes ME, Wögenstein GM, Colombo G, Casado-Polanco R, Siegert S, “Optimizing AAV2/6 microglial targeting identified enhanced efficiency in the photoreceptor degenerative environment”, Mol Ther Methods Clin Dev, 2021; 23:210-224, https://doi.org/10.1016/j.omtm.2021.09.006

2019

Maes ME, Colombo G, Schulz R, Siegert S, “Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges”, Neuroscience Letters, 2019; 707:134310, https://doi.org/1016/j.neulet.2019.134310

Peer-reviewed research articles before independent research group:

2016

Tsai L-H, Siegert S, “How microRNAs are involved in “splitting the mind”, JAMA Psychiatry, 2016; 73(4): 409-10, https://doi.org/10.1001/jamapsychiatry.2015.3144

2015

Mungenast AE*, Siegert S*$, Tsai L-H, “Modeling Alzheimer’s disease with human induced pluripotent stem (iPS) cells”, Molecular and cellular neuroscience 2015; 73:13-31, https://doi.org/10.1016/j.mcn.2015.11.010 

Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai L-H, “The schizophrenia risk gene miR-137 alters presynaptic plasticity”, Nature Neuroscience 2015; 18(7): 1008-16, https://doi.org/10.1038/nn.4023

Rei D, Mason X, Gräff J, Seo J, Rudenko A, Wang J, Rueda R, Siegert S, Cho S, Canter RG, Mungenast A, Deisseroth K, Tsai L-H, “The BLA bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway”, Proc Natl Acad Sci USA 2015; 112(23): 7291-6, https://doi.org/10.1073/pnas.1415845112

2012

Siegert S, Cabuy E, Gross Scherf B, Kohler H, Panda S, Le, Y-Z, Fehling HJ, Gaidatzis D, Stadler M, Roska B, “Transcription factor code and disease map for retinal cell types”, Nature Neuroscience 2012; 15(3): 487-95, https://doi.org/10.1038/nn.3032

2010

Busskamp V, Duebel J, Balya D, Fradot M, Viney TJ, Siegert S, Groner AC, Cabuy E, Forster V, Seeliger M, Biel M, Humphries P, Paques M, Mohand-Said S, Trono D, Deisseroth K, Sahel JA, Picaud S, Roska B, “Genetic reactivation of cone photoreceptors restores complex visual responses in Retinitis pigmentosa”, Science 2010; 329(5990): 413-7, https://doi.org/10.1126/science.1190897

2009

Siegert S, Gross Scherf B, Del Punta K, Didkovsky N, Heintz N, Roska B, “Genetic address book for retinal cell types”, Nature Neuroscience 2009; 12(9): 1197-204, https://doi.org/10.1038/nn.2370   

Münch TA, da Silveira RA, Siegert S, Viney TJ, Awatramani GB, Roska B, “Approach sensitivity in the retina processed by a multifunctional neuronal circuit”, Nature Neuroscience 2009 Oct;12(10):1308-16. https://doi.org/10.1038/nn.2389        

2007

Viney TJ, Balint K, Hillier D, Siegert S, Boldogkoi Z, Enquist LW, Meister M, Cepko CL Roska B, “Local retinal circuits of melanopsin-containing ganglion cells identified by transsynaptic viral tracing”, Current Biology 2007 Jun 5; 17(11): 981-8 https://doi.org/10.1016/j.cub.2007.04.058

2006

Siegert S, Schnierle P, Schnierle BS, “Novel anti-viral therapy: Drugs that blocks HIV entry at different target sites”, Mini Reviews in Medicinal Chemistry 2006 May; 6(5): 557-62. Review, https://doi.org/10.2174/138955706776876267

2005

Siegert S, Thaler S, Wagner R, Schnierle BS, “Assessment of HIV-1 entry inhibitors by MLV/HIV-1 pseudotyped vectors“, AIDS Research and Therapy 2005 Sep 12, 2:7 https://doi.org/10.1186/1742-6405-2-7